Several cases of transient leukopenia have been reported in patients receiving silver sulfadiazine therapy. The use of SILVADENE Cream 1% (silver sulfadiazine) in some cases of glucose-6-phosphate dehydrogenase-deficient individuals may be hazardous, as hemolysis may occur. However, the incidence of clinically reported fungal superinfection is low. If allergic reactions attributable to treatment with silver sulfadiazine occur, continuation of therapy must be weighed against the potential hazards of the particular allergic reaction.įungal proliferation in and below the eschar may occur. There is potential cross-sensitivity between silver sulfadiazine and other sulfonamides. Some of the reactions, which have been associated with sulfonamides, are as follows: blood dyscrasias including agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia, and hemolytic anemia dermatologic and allergic reactions, including life-threatening cutaneous reactions gastrointestinal reactions hepatitis and hepatocellular necrosis CNS reactions and toxic nephrosis. Although few have been reported, it is possible that any adverse reaction associated with sulfonamides may occur. Silver sulfadiazine is not a carbonic anhydrase inhibitor and may be useful in situations where such agents are contraindicated.Ībsorption of silver sulfadiazine varies depending upon the percent of body surface area and the extent of the tissue damage. Results of In Vitro Testing with SILVADENE ® Cream 1% (silver sulfadiazine) Concentration of Silver Sulfadiazine Number of Sensitive Strains/Total Number of Strains Tested Genus & Species ![]() Silver sulfadiazine acts only on the cell membrane and cell wall to produce its bactericidal effect. Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemical techniques have revealed that the mechanism of action of silver sulfadiazine on bacteria differs from silver nitrate and sodium sulfadiazine. Sufficient data have been obtained to demonstrate that silver sulfadiazine will inhibit bacteria that are resistant to other antimicrobial agents and that the compound is superior to sulfadiazine. Results from in vitro testing are listed below. It is bactericidal for many gram-negative and gram-positive bacteria as well as being effective against yeast. Do not use in large quantities, particularly over raw surfaces or blistered areas.Silver sulfadiazine has broad antimicrobial activity. Children under 2 years of age, consult a physician. A Must have for your First Aid Kit.Īpply to affected area not more than 3 to 4 times daily. ALOE GEL has a cooling effect on the itchy hot skin and promotes healing while the Lidocaine decreases healing time while stopping the burning fast.EASY TO APPLY generously to the burned area up to 4 times daily, Treat Any Burn even 1st degree burns, clear gel, immediate burn relief, little to no smell, Recommended for Children and Adults.RECOMMENDED BY PHYSICIANS AND PHARMACISTS to use on First Degree Burns and including: Sunburn, Kitchen Burns, Electricity burns, heat, light, Itches, Rashes, Bug Bites, Shingles and much more. ![]() WITH THE 4% LIDOCAINE, which is the maximum percentage of Lidocaine allowed by the US FDA for over the counter products, it relieves pain fast while soothes the skin and helps with fast itch relief.Soothing Aloe Gel and Vitamin E, assists the healing process. ALOCANE BURN GEL is a water based formula with an efficient proprietary transfer vehicle that quickly absorbs deep into the layers of skin.Look no further than ALOCANE Maximum Strength Emergency Burn Gel for fast, immediate burn pain relief. No other burn treatment gel available offers the same concentration of 4% lidocaine without a prescription.Ĭontains Aloe Vera as well as Vitamin E, which both help soothe and replenish damaged skin.ĭon't get burned by home remedies or other gels that contain alcohol or petroleum. ALOCANE is made with 4% lidocaine, the maximum strength allowed by the FDA, to provide instant relief and stop burn pain on contact. Instead, ALOCANE is made with natural ingredients to soothe, heal and protect injuries as well as stop pain and sensitivity on contact. Unlike other burn treatment gels, ALOCANE does not contain harmful ingredients and irritants like petroleum, alcohol or menthol. ALOCANE Maximum Strength Emergency Burn Gel alleviates common burns, sunburns, insect bites and minor cuts and scrapes fast with the help of the pain-stopping power of 4% lidocaine, soothing aloe vera and healing vitamin E. ALOCANE Maximum Strength Emergency Burn Gel utilizes the most effective ingredients to numb, treat and heal minor burns of all types.
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